Pentamidine is active in a neutropenic murine model of acute invasive pulmonary fusariosis.
نویسندگان
چکیده
We studied the efficacy of pentamidine (PNT) as prophylaxis or early treatment in acute pulmonary fusariosis in neutropenic mice. PNT-preexposed mice had significantly improved survival and reduced fungal burden compared to amphotericin B-preexposed and untreated mice. PNT-treated mice had increased survival but no difference in fungal burden versus untreated mice.
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 50 1 شماره
صفحات -
تاریخ انتشار 2006